What is Lymphogranuloma Venereum LGV ?

What is the disease Lymphogranuloma venereum (LGV)? LGV including a group of sexually transmitted diseases (Sexually Transmitted Disease, STD) which is widespread throughout the world. The disease is caused by Chiamyidia lakvlaki trachomatis attacking people and women. LGV is referred to as the sixth venereal disease.

Chiamydia trachomatis is a bacterium that was first called as a large-sized viruses, intracellular living in leukocytes and can be cultured in the yolk sac of eggs and white rat brain. This group of viruses can also cause psittacosis, trachoma and inclusion conjunctivitis.

LGV transmission, LGV is transmitted from person to person by direct contact with lesions, ulcers or areas that contained the bacteria. Because the transmission of the organism occurs through sexual intercourse (vaginal, oral, or anal) and also occur through skin contact with the skin.

Clinical symptoms and diagnosis of LGV, After an incubation period of 3-30 days, an early sign of LGV in the form of a primary lesion shaped papule or ulcer in the entry of germs, small contained in the genital or rectal area. Ulcers are present in the urethra, vagina or rectum rarely detected. Moreover enlargement of lymph glands in the genital area (which occurs after the ulcer healed), bleeding, pain or discharge exudate and ulceration. LGV is difficult to distinguish genital lesions and ulcers that occur in syphilis, genital herpes or chancroid.

If left untreated, LGV will experience complications, such as enlargement and external genital ulceration and lymphatic obstruction causing genital elephantiasis. In patients with elephantiasis female labia associated with ulceration of the vulva and rectum (genito-anorectal syndrome). In patients la-la ki ki may occur elephantiasis of the penis and scrotum, and stricture and fistula that causes non-gonococcal urethritis.

LGV diagnosis is mainly based on complaints and clinical symptoms occur. To confirm the diagnosis of LGV should be found to the causative organism, by inoculation of pus from the lesion into yolc egg sac containing the embryo or into the brains of mice. With Giemsa staining on smear or biopsy results gland lesions, the organism can be found in the intracytoplasmic inclusion body. Can be done to help diagnose skin test (Frei-Hoffmann Test) or serology for example, complement fixation test.

Treatment and prevention of LGV, LGV can be treated with doxycycline for 21 days, erythromycin or azithromycin. Doxycycline should not be given to pregnant women or mothers who breastfeed their children.
Surgery can be performed if the patient is being treated with antibiotics, for example, to remove the abscess pus by aspiration, excision of rectal stricture, vulvektomi case of genital elephantiasis.

Prevention is by no sexual contact precautions and sexually transmitted diseases (STD) other.

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